I’ve spent the past 5 years working to recover my ability to rest in a squat. Not quite there yet, but getting closer. (Photo by Jackie Brewer.)

When the tribespeople squatted, their readouts pinged, indicating that their leg muscles were contracting far more than when they sat, and almost 40 percent as often as during walks.

Source: Sitting Is Bad for Our Health. Should We Squat More Instead?

Probably just another instance of “people who drink moderately have other healthy behaviors as well,” but very much in keeping with my preconceptions:

Compared with abstainers, those who drank one to 13 standard drinks a week had a 66 percent lower rate of beta amyloid deposits in their brains.

Source: Moderate Drinking Tied to Lower Levels of Alzheimer’s Brain Protein – The New York Times

I’ve been lifting weights for decades. I was pretty consistent about it for a long time. For years while I was working at a regular job, Jackie and I would go to the Fitness Center and lift before I went to the office at least two, often three times a week, using whatever machines they had (three or four different brands/styles of machines over the years). I saw pretty good gains the first six weeks or so that I was doing this, but they leveled off. I kept at it for years after that, with very little to show for it.

All that time I imagined that the issue was intensity—to make more gains, I needed to lift more and harder. I now think that was wrong. I think the problem was just that machines are a crappy way to build strength or muscle.

Four and a half years ago we moved to Winfield Village, which has a pretty good set of free weights. I’ve been using them—once again without much to show for it. In this case, the issue is not a matter of using the wrong equipment or a lack of intensity—it’s that my consistency has fallen off. I get on a schedule of lifting two or three times a week, but only keep it up for a week or two and then miss a few workouts.

Happily, this month I’m doing pretty well. In 21 days I’ve gotten in 9 lifting sessions, which is just about exactly my target. (I aim for every other day, so when I miss an occasional day it still comes in at 3 times a week.)

I’m seeing some nice strength gains (although after just three weeks I can’t be sure I’m not back in the situation of “anything will build strength for six weeks”). I’m also putting on some weight—probably just because I’ve been eating too many carbs, which I’ll fix here shortly, but in the meantime I’m choosing to imagine that I’m adding some muscle as well.

Understanding that consistency is the key, maybe I’ll be able to keep it up. (Watching my older relatives become frail due to sarcopenia, I’m determined to avoid that fate.)

I’m pretty sure I’ll manage okay until the weather turns and I have to start balancing the lifting with the running and hiking. (I’ve only gotten in one run this month, because of ice and cold.) We’ll have to see after that. But as I say, I’m determined.

Some years back, after I’d finally made some real progress at losing weight and getting in shape, I was thinking of writing a post about it, when an on-line acquaintance posted a stern note to the effect that she didn’t want to see any “weight-loss success stories” from anyone who hadn’t kept the weight off for five years.

It’s a reasonable perspective. Almost any weight loss program will work for six months. Almost nobody who undertakes such a program manages to get down to a normal weight and maintain that weight for five years.

Despite the aforementioned reasonableness, I was somewhat put off by her attitude. Who was she to tell me when and how I could tell my own story? (To be fair, she wasn’t telling me I couldn’t tell my story, just that she didn’t want to see it.)

That feeling of being just a tiny bit stifled made the whole thing stick in my mind, such that I’ve kept track: February 14th, 2015 was when my BMI dropped from 25 (overweight) to 24.9 (normal weight). It has now been in the “normal weight” range for five years.

I didn’t stop there. I continued losing weight for almost two more years, until in December 2016 I decided that I didn’t want to get any smaller. At that point I started targeting a stable weight (145 lbs, which gives me a BMI right at the midpoint of the “normal weight” range). I’ve achieved my target pretty well, keeping my weight to within plus-or-minus about 3 pounds of my target.

My weight going back to January 2000. The faint gray shows my actual measured weight. The bolder red line is a logarithmic moving average “trend weight.” The big gap is from when I lost access to the good doctor’s scale at the Motorola office in mid-2007 until I bought a good digital scale in mid-2011.

I wish I had something useful to say about how to lose weight, but I really don’t.

I lost the first fifty pounds the long, slow, hard way—eating less (portion control) and moving more. Because it was hard—I was hungry all the time—I knew that even a slight misstep could easily see me gaining back back all that weight. At that point I did an experiment with low-carb eating, to see if it would address some health issues unrelated to my weight, and quickly peeled off another 15 pounds.

Since then I’ve been eating what I call a “carb-aware whole-foods diet,” meaning that my main focus is on eating food (and refraining from eating industrially produced food-like substances), but purposefully keeping my carbs down in the 100–125 grams per day range, and taking my carbs down lower if my weight gets up above where I want it.

Because eating low-carb worked well for me, I’m modestly inclined to be a booster of the diet, but only modestly. Who am I to say that just because it worked for me it would work for anyone else?

Besides eating actual food and watching my carbs, anybody who reads my blog knows that I spend a lot of time moving. Just click on the “exercise” tag or the Fitness category to see post after post talking about my efforts to get enough exercise (in the old days), and see how they gradually changed into my efforts to keep moving throughout the day. It’s common knowledge that you can’t exercise your way out of a bad diet, but I think it’s also true that moving throughout the day is critical to achieving and maintaining good health.

When you feel sick, you prefer to sit still. This behavior pattern is not only well known, it even has a name: “inflammatory-induced sickness behavior.”

In the modern world this easily leads to a particularly pernicious vicious cycle. Modern lifestyles lead to metabolic syndrome. Metabolic syndrome produces systemic inflammation, which makes you feel like sitting still. Wanting to sit still makes what would otherwise be the most potent tool for reducing systemic inflammation—exercise—tough to bring to bear.

This rather dense article from back in 2010 describes the problem: Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle. It also proposes a category of solutions: hormesis. That is to say, any of a set of mild metabolic stresses that prompt a response greater than “just enough” to stave off the damage produced by the stress itself.

The result is less systemic inflammation, and therefore less inflammatory-induced sickness behavior, hence an increased inclination to move.

Or, as they say:

We therefore propose that exercise salience, the motivation to undertake physical activity, is modulated by the inflammatory status of an animal, decreasing in an inflammatory phenotype, including the metabolic syndrome and increasing in an anti-inflammatory “healthy” phenotype. The type of phenotype may well be determined by the degree of hormesis, as metabolic stressors, such as exercise, plant polyphenols and calorie restriction tend to induce an anti-inflammatory phenotype.

Besides exercise, the article suggests two other broad categories of available hormetins.

One is related to food, and consists of the obvious stuff that everybody knows: Avoid industrially produced edible substances. Consider such modalities as time-restricted eating, calorie restriction, or fasting. Include foods rich in plant polyphenols. (In other words, “Eat food, not too much, mostly plants.”)

The other is related to temperature: Expose yourself to mild cold and/or heat stress. (Spend time outdoors in the winter. Take a cold shower. Spend time outdoors in the summer. Take a sauna.)

Each of these things will produce some mild metabolic stress. As long as you don’t overdo it, that mild stress will produce a stress response greater than necessary to handle the stress itself, with the side-effect of bringing down systemic inflammation. With the systemic inflammation eased, you’ll start feeling like moving again. That puts the potent tool of exercise back on the table.

Nature has a more recent article on all this stuff, which is sadly behind a paywall.